Case Report
Rhabdomyolysis Induced by Coadministration of Fusidic Acid and Atorvastatin: A Case Report and Comprehensive Review of the Literature
Table 2
Summary of the published case reports highlighting the discussed drug-drug interaction.
| Authors | Statin | Fusidic acid in therapeutic dosage | Indication for fusidic acid administration | Outcome |
| Bachoumas et al. [10] | Pravastatin | ✓ | MSSA positive abscess of the tibial plate | Death |
| Wenisch et al. [11] | Atorvastatin | ✓ | S. aureus and E. coli-infected gangrenous foot lesion | Discharged home with restored mobility |
| Gabignon et al. [12] | Atorvastatin | ✓ | MSSA positive hip prosthetic joint infection | Discharged home with restored mobility |
| Nandy and Gaïni [13] | Atorvastatin | ✓ | Infected aortic aneurysm, with involvement of the endovascular stent and para-aortic abscesses | Discharged home with improved mobility |
| Cowan et al. [4] | Atorvastatin/rosuvastatin | ✓ | MSSA positive hip prosthesis | Death |
| Burtenshaw et al. [14] | Simvastatin | ✓ | Isolation of MRSA from aneurysmal sac after elective AAA repair | Death |
| Teckchandani et al. [5] | Atorvastatin | ✓ | Infected hip prosthesis | Discharged home with restored mobility |
| O’Mahony et al. [15] | Atorvastatin | ✓ | NP | Discharged home with restored mobility |
| Saeed and Azam [6] | Atorvastatin | ✓ | Postarthroscopy MRSA right knee infection | Discharged home with improved mobility |
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NP: not provided.
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