Fatal Pneumococcus Sepsis after Treatment of Late Antibody-Mediated Kidney Graft Rejection

Figure 2

Histologic assessment of renal transplant biopsy. The biopsy showed signs of chronic-active antibody-mediated rejection with severe tubular damage, interstitial edema, and peritubular capillaritis ((a) arrowheads); glomerulitis with double contours ((b) arrowheads); diffuse positive C4d staining in peritubular capillaries (c); and interstitial fibrosis with severe arteriosclerosis (d). ((a) H&E, (b) and (d) Jones methenamine, and (c) C4d immunohistochemistry; original magnification: (a) and (b) ×60, (c) ×20, and (d) ×40).

(a)

(b)

(c)

(d)