Case Report

Clinicopathological Implications of Proteinuria after Long-Term Isolated Hematuria due to Thin Basement Membrane Nephropathy and Focal Segmental Glomerulosclerosis

Figure 1

Kidney biopsy findings. (a): Light microscopic observation reveals glomeruli with slight enlargement. Periodic acid-Schiff staining. Original magnification ×200. (b) One glomerulus with focal segmental sclerosis is found at a corticomedullary junction area (arrow). *; arcuate artery. Periodic acid-Schiff staining. Original magnification ×200. (c) This glomerulus shows perihilar type of segmental sclerosis. Periodic acid-methenamine-silver staining. Original magnification ×200. (d) Immunofluorescent finding shows linear alpha-2 (red) and alpha-5 (green) of type IV collagen staining along the glomerular basement membrane. Yellow stain indicates merged image of co-localization of alpha-2 (red) and alpha-5 (green) of type IV collagen.
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