|
| Author | Tumour | Presentation | CSF | NCS | Imaging | Anti-GQ1b | Outcome | Postmortem findings if performed |
|
| Guarino et al. [50] | Stomach adeno-carcinoma | Six months after gastrectomy with three days of diplopia, occipital headache. OE: bilateral VI nerve palsies, severe ataxia, and global areflexia | Prot 0.6#x2009;g/L,
WCC-1/mL, glu-0.34 g/L.
cytology adenocarcinomatous cells | — | CT normal | — | Treated with chemotherapy but worsened and died 20 days later | — |
| Myeloma | 4 days of diplopia and diffuse arthralgia. Past history of thyroidectomy for cancer 4 years prior and AML 2 years prior. OE: bilateral III nerve palsies, ataxia, and global areflexia | Prot 1 g/L,
WCC-290/mL (lymphs),
glu-“normal”,
Cytology myeloblasts | — | CT normal | — | Treated with intrathecal chemotherapy but died 40 days later | — |
|
| Nakatsuji et al. [51] | Signet ring adeno-carcinoma of unknown primary | One month progressive diplopia and unsteadiness. OE: bilateral opthalmoplegia, sluggish pupil light responses, hypo/areflexia, ataxia, and decreased sensation | Opening pressure 12 cm/H20,
Prot 2.7 g/L
WCC 51 (65% lymphs, 35% polys),
Glu-6.4 g/L,
Cytology negative | Absent sural/ tibial potentials, and normal motor conduction | MRI with contrast enhancement of III, IV, VI, XII, pons | | Rx with IvIg but worsened and died nine weeks after admission | Brain leptomeningeal, cranial nerve, and choroid plexus dissemination of signet right adenocarcinoma |
|
| Csépány et al. [52] | Bronchial adeno-carcinoma | Five days of clumsiness of the right arm, double vision, and unsteadiness. OE: right VI nerve palsy, bilateral VII, decreased reflexes, and ataxia | Glu 3.1 g/L,
WCC 256 (20% lymphs, 48% macros, 12% monos, 20% large atypical cells, and a few signet ring cells | Mild axonal sensory-motor neuropathy | CT contrast-right sylvian fissure enhancement. MRI few small enhancing cortical regions.
CT chest, small lung tumour | — | — | — |
|
