|
| Author | Tumour | Presentation | CSF | NCS | Imaging | Anti-GQ1b | Outcome | Postmortem findings if performed |
|
| Tahrani et al. [57] | Anaplastic adenocarcinoma of pancreas | Two weeks of worsening mobility and diplopia O/E: bilateral ophthalmoplegia, L LMN VII, areflexia, and generalised weakness | Prot 0.65, WCC 12 (lymphocytes) | — | Non contrast
MRI
NAD | −ve | Died | Yes but brain not studied |
|
| Aki et al. [56] | Chronic lymphocytic leukaemia | Neutropaenia and fever during chemotherapy with diplopia and arm weakness O/E: areflexia, ophthalmoplegia, dysphagia, dysarthria, shoulder weakness, and ataxia | NAD | Axonal sensory motor neuropathy | MRI
NAD | −ve | Plasmapheresis with total improvement | — |
|
| Gentile et al. [55] | Burkitt’s lymphoma | Diplopia
O/E: bilateral ophthalmoplegia, areflexia, and gait ataxia | Prot 1.45, no cells, cytology negative | Diffuse axonal neuropathy | MRI
NAD | −ve | Some improvement with chemotherapy | — |
|
| De Toni et al. [54] | Squamous cell carcinoma of lung | Progressive hand and feet numbness, unsteady gait
O/E: general weakness, sensory ataxia, impaired sensation to all modalities, and areflexia | Protein 0.9, WC 14, no cytology | Diffuse axonal sensory polyneuropathy | — | +ve and on lung histology | IVIg, slowly worsened and progressed | — |
|
| Rubio-Nazabal et al. [53] | Hodgkin’s lymphoma | Fever and weight loss then bilateral diplopia, photophobia, dysphonia, and gait instability on chemotherapy
O/E: ophthalmoplegia, fixed and dilated pupils, dysphonia, mild dysphagia, VII palsy, and ataxia | Protein 0.79, WCC 2, normal lymphocytes on cytology | Axonal sensory neuropathy | MRI with contrast NAD | +ve | IVIg, slowly improved over 2 weeks | — |
|
