Intracranial Metastatic Neuroblastoma Treated with Gamma Knife Stereotactic Radiosurgery: Report of Two Novel Cases

Table 1

Comparison between modalities of radiation therapy for CNS neuroblastoma.

First author, year	No. of patients	Tumor pathology	Modality	Dosage	Time to recurrence/death
Oyama et al., 2005 [9]	1	Primary intrasellar neuroblastoma	GKSRS, CRT	15 Gy, 50 Gy	48 mo, 3 mo (NPALF)
Unger et al., 2005 [11]	14	Esthesioneuroblastoma	GKSRS	15–34 Gy	6–79 mo
Sakurada et al., 2007 [10]	1	Primary 4th ventricular neuroblastoma (transformed from neurocytoma)	GKSRS, WBRT	ND, 30 Gy	96 mo (PNAD)
Croog et al., 2010 [12]	29	Recurrent cerebral neuroblastoma	CSI CRT	1260–2160 cGy	1.5–63 mo

GKSRS: Gamma Knife Stereotactic Radiosurgery; GY: Gray; CRT: conventional radiation therapy; NPALF: no progression at last followup; WBRT: whole brain radiotherapy; ND: not documented; PNAD: progression noted at death; CSI: craniospinal irradiation; Cgy: centiGray.