Role of Carbamazepine in the Symptomatic Treatment of Subacute Sclerosing Panencephalitis: A Case Report and Review of the Literature

Table 1

Summary of case series documenting use of carbamazepine therapy in the treatment of SSPE.

Number of patients	Patient age (years)	Case description summary	Reference
3	13, 13, 9	All 3 patients showed dramatic improvement in myoclonus that was temporary. One patient discontinued therapy because of carbamazepine allergy	[13]
1	26	Temporary improvement of myoclonus, followed by deterioration and death	[14]
1	17	Dramatic improvement of myoclonus, worsened on discontinuation of carbamazepine	[15]
1	30	Temporary improvement with carbamazepine	[16]
1	20	Dramatic improvement of myoclonus that worsened upon carbamazepine discontinuation	[12]
1	9	No response to carbamazepine therapy	[17]
1	4	No improvement on carbamazepine, improvement with topiramate	[18]