356526.fig.003a
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356526.fig.003b
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Figure 3: Microscopic image of the patient’s GBM. (a) Low-power micrograph of hemotoxylin and eosin staining, showing cellular atypia, glomeruloid vascular pattern, and areas of tumor necrosis diagnostic of GBM. (b) High-power micrograph showing atypical, hyperchromatic nuclei and numerous mitotic figures. (c) Low-power micrograph showing numerous cells staining positive for Ki67, a marker of cell proliferation. (d) Low-power micrograph showing staining for glial fibrillary acidic protein (GFAP).