Persistent Cryptococcal Brain Infection despite Prolonged Immunorecovery in an HIV-Positive Patient
Figure 2
(a) Brain biopsy taken in December 2005, 4 months after initial presentation showing reactive gliosis and focally distended perivascular spaces containing Cryptococcus. (b) Brain biopsy taken in December 2006, 16 months after initial presentation showing encapsulated, budding yeast forms, scattered singly with some surrounding necrosis and moderate chronic inflammation. No granulomata were seen.
