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Author | | Age at MS onset | Age at tumor diagnosis | MS course | Tumor clinical presentation | MRI main features (other than typical MS findings) | Histopathology |
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Khan et al. [5] | | 43 | 51 | RRMS | No symptoms (suspicion based on routine MRI) | 3 cm enhancing lesion involving both white and gray matter in the right parietal lobe* | Monomorphic neoplasm composed of oligodendrocytes, GFAP positive, and CD68 negative |
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Green et al. [6] | Case | 34 | 50 | RRMS | No symptoms (suspicion based on routine MRI) | Nonenhancing mass lesion involving white matter in the right temporoparietal area, with some sulcal effacement of the overlying cortex* | Microcystic low grade oligodendroglioma |
Case |
44? | 44? | N/A | Seizures and monocular inferior left scotoma | Right temporal lobe lesion with some mass effect* | Grade 2 oligodendroglioma |
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Giordana et al. [3] | | 34 | 42 | PPMS | N/A | Bilateral frontal lesion, involving anterior corpus callosum | Unclear grade oligodendroglioma, not contiguous with MS lesions |
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Rao et al. [4] | | N/A | 65 | N/A | N/A | Diffuse lesion (right > left) across corpus callosum | Oligodendroglioma with spotty calcification, ring lesions, contiguous with MS plaques |
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Barnard and Jellinek [2] | | 28 | 43 | RR/SC MS | N/A | Mass lesion at the right temporal lobe | “Polymorphic” oligodendroglioma with mitotic figures and central necrosis |
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de la Lama et al. [7] | | 26 | 37 | RRMS | Seizures | Large subcortical lesion at the right frontal lobe, poorly enhancing, causing mass effect and midline shifting to the left* | Tumoural proliferation with homogeneous nuclei and clear cytoplasms, not contiguous with MS plaques—grade C oligodendroglioma (Smith classification) |
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