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| Case 1 | Case 2 | Case 3 |
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Age | 40 | 24 | 51 |
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Gender | F | F | M |
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Occupation | Housewife | Amanuensis | Worker of pottery |
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Comorbidities | Systemic sclerosis with Raynaud’s syndrome (pulmonary tuberculosis, Herpes zoster, inactive) | Systemic lupus erythematosus | Bronchial asthma, pneumoconiosis, pulmonary tuberculosis, inactive, pseudomembrane colitis, colon adenocarcinoma |
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Immunosuppression agent | Steroids | Steroids | Steroids |
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Initial symptoms and signs | Fever; unsteady gait | Right facial spasm with dull pain; slurred speech; afebrile leukocytosis | Fever with leukocytosis; quadriplegia; seizure attacks |
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Abscess number | Multiple | Multiple | Multiple |
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Abscess size (in the largest diameter, mm) | 10 | 30 | 30 |
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Abscess progression | Yes | Yes | Yes |
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Abscess localization | L, F, P | B, T, O | B, T, F, P |
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Following treatment | Change to second-line antibiotics | Change to second-line antibiotics; stereotaxic aspiration; craniotomy | Refused craniotomy |
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3-month outcome | Right hemiplegia | Homonymous hemianopia; alexia | Death |
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1-year outcome | Death | Homonymous hemianopia; alexia | Death |
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Other sites involved | Nil | Nil | Nil |
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aDuration from symptoms onset to diagnosis (day) | 14 | 7 | 38 |
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Antibiotics for abscesses | Oxacillin; ceftriaxone; imipenem; sulfamethoxazole/trimethoprim | Sulfamethoxazole/trimethoprim; meropenem trihydrate; amikacin | Sulfamethoxazole/trimethoprim |
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Duration of antibiotics use (day) | 75 | 294 | 4 |
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Surgical intervention | Craniotomy with guided sonography for the aspiration of the abscesses | Craniotomy with guided sonography for the aspiration of the abscesses | Stereotaxic aspiration |
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