Delayed Cerebral Radiation Necrosis after Neutron Beam Radiation of a Parotid Adenocarcinoma: A Case Report and Review of the Literature
Figure 4
Formalin fixed, paraffin embedded tissue sections stained with hematoxylin and eosin demonstrate reactive astrogliosis, radiation-induced vasculopathy, and necrosis. (a) Reactive astrocytes show hypertrophic, eosinophilic cytoplasm with eccentrically placed nuclei. (b) Higher magnification of inset in (a). (c) Hyalinized arterioles are seen, characteristic of radiation-induced vasculopathy. (d) Higher magnification image of (c). Radiation necrosis is demonstrated at (e) interface of brain and necrotic area and (f) necrosis in the center of the lesion.
