Case Report
Imaging Evidence for Cerebral Hyperperfusion Syndrome after Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke
Table 1
Four cases of cerebral hyperperfusion syndrome after intravenous tPA for acute ischemic stroke.
| | Age | Sex | Stroke symptoms | PMH | NIHSS (onset) | tPA dose | CHS symptoms | NIHSS (D/C) | Infarct area |
| Case 1 | 61 | M | Aphasia, right hemiplegia | CLL | 9 | 90 mg | Seizure | 2 | Cortical | Case 2 | 82 | M | Dysarthria, right hemiplegia | Prostate cancer. HTN, Afib | 9 | 70 mg | Worsening hemiplegia | 7 | Basal ganglia | Case 3 | 92 | M | Aphasia, right hemiplegia, confusion | Colon cancer, Afib | 23 | 74 mg | Worsening hemiplegia | Deceased | Cortical | Case 4 | 65 | F | Aphasia, right hemiplegia | HTN, DVT, colitis | 20 | 90 mg | Eyes deviation, confusion | 10 | Cortical |
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PMH: past medical history; NIHSS: NIH stroke scale; CHS: cerebral hyperperfusion syndrome; D/C: at discharge time; M: male; F: female; CLL: chronic lymphocytic leukemia; HTN: hypertension; Afib: atrial fibrillation; DVT: deep vein thrombosis.
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