Imaging Evidence for Cerebral Hyperperfusion Syndrome after Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke

Table 1

Four cases of cerebral hyperperfusion syndrome after intravenous tPA for acute ischemic stroke.

	Age	Sex	Stroke symptoms	PMH	NIHSS (onset)	tPA dose	CHS symptoms	NIHSS (D/C)	Infarct area
Case  1	61	M	Aphasia, right hemiplegia	CLL	9	90 mg	Seizure	2	Cortical
Case  2	82	M	Dysarthria, right hemiplegia	Prostate cancer. HTN, Afib	9	70 mg	Worsening hemiplegia	7	Basal ganglia
Case  3	92	M	Aphasia, right hemiplegia, confusion	Colon cancer, Afib	23	74 mg	Worsening hemiplegia	Deceased	Cortical
Case  4	65	F	Aphasia, right hemiplegia	HTN, DVT, colitis	20	90 mg	Eyes deviation, confusion	10	Cortical

PMH: past medical history; NIHSS: NIH stroke scale; CHS: cerebral hyperperfusion syndrome; D/C: at discharge time; M: male; F: female; CLL: chronic lymphocytic leukemia; HTN: hypertension; Afib: atrial fibrillation; DVT: deep vein thrombosis.