Case Report

Unusual Spread of Renal Cell Carcinoma to the Clivus with Cranial Nerve Deficit

Table 2

Cases of clival metastasis available from PubMed (and other databases) along with the primary and presentation.

Author(s)Year of reporting PrimaryPresentation

Turner et al. [6] 1980Ewing’s sarcoma (femur)Diplopia
Fumino et al. [4]1998Renal cell carcinomaDiplopia
Ulubas et al. [7]2005Lung cancer (SCC)Headache
Escarda et al. [8] 2006Hepatocellular carcinomaDiplopia
Malloy [9]2007Prostate cancer (adenocarcinoma)Diplopia
Marchese-Ragona et al. [10]2008Cancer of the tonsil (SCC)Diplopia
Pallini et al. (case series) [2]2009Lung cancer (adenocarcinoma) ()
Lung cancer (SCC) ()
Prostate cancer (adenocarcinoma) ()
Melanoma (skin) ()
Diplopia
Kolias et al. [11] 2010Prostate cancer (adenocarcinoma)Multiple cranial neuropathy
Ng et al. [12] 2011Breast cancerOphthalmoplegia
Fukushima et al. [13]2012Stomach cancer (signet ring cell carcinoma)Headache and diplopia
Bohnstedt et al. [14]2012Soft tissue myoepithelium (left hip)Ophthalmoplegia
Kendre et al. [15]2014Rectal carcinomaDiplopia
Mendelson et al. [5]2015Renal cell cancerDiplopia
Kapoor et al. [16]2015Breast cancerDiplopia
Rao et al. [17]2015Cervical cancer Headache and vomiting
Lee et al. [18]2015GastroadenocarcinomaDiplopia
Okudo et al. (present case)2016Renal cell carcinomaDiplopia

SCC: squamous cell carcinoma.
This table was adapted with permission from Kapoor et al. [16].