Hyperechogenicity of the Substantia Nigra in Parkinson’s Disease: Insights from Two Brothers with Markedly Different Disease Durations

<div>Transverse view of substantia nigra (SN) morphology in Patients 1 and 2 using transcranial sonography. Images of the right (top) and left (bottom) SN are shown. Solid line encircles the mesencephalic brainstem. Dotted line encircles the SN. White rectangles correspond to the placement of the probe.</div>

Case Reports in Neurological Medicine

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Figure 1

Figure 1: Hyperechogenicity of the Substantia Nigra in Parkinson’s Disease: Insights from Two Brothers with Markedly Different Disease Durations 