Differential Effects of Awake Glioma Surgery in “Critical” Language Areas on Cognition: 4 Case Studies
Table 1
Demographic and clinical characteristics. Y = years, Hem. Dom. = hemispheric dominance, M = male, L = left, R = right, AF = arcuate fasciculus, O = oligodendroglioma, GBM = glioblastoma, AO = anaplastic oligodendroglioma, EoR = extent of resection, and AED = antiepileptic drugs.
Case
Gender
Age (y)
Education (y)
Handedness
Onset symptoms
Hem. Dom.
Cortical area
Subcortical area
WHO grade (2007)
Histology
EoR (%)
AED
Adjuvant therapy
P1
M
45
15
L
Seizure
L
Temporoparietal (“Wernicke”)
AF
II (low)
O
58.34
Yes
Radio
P2
M
63
12
R
Language problems
L
Temporoparietal (“Wernicke”)
AF
IV (high)
GBM
88.68
Yes
Radio
P3
M
41
16
R
Seizure
L
Frontal and insular (“Broca”)
AF
II (low)
O
52.73
Yes
No
P4
M
33
15
R
Seizure
L
Temporoparietal and frontal (“Wernicke” and “Broca”)
