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Case Reports in Obstetrics and Gynecology
Volume 2012 (2012), Article ID 137861, 4 pages
http://dx.doi.org/10.1155/2012/137861
Case Report

Management of a Pregnancy Complicated by Pompe Disease

1Division of Clinical and Biochemical Genetics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, 975 West Walnut Street, IB 130, Indianapolis, IN 46202, USA
2Department of Neurology, Indiana University School of Medicine, 975 West Walnut Street, IB 130, Indianapolis, IN 46202, USA
3Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Indiana University School of Medicine, 975 West Walnut Street, IB 130, Indianapolis, IN 46202, USA

Received 18 October 2012; Accepted 21 November 2012

Academic Editors: J. C. Canterino, T. Guvenal, H.-C. Lai, A. Ohkuchi, and S. Rasmussen

Copyright © 2012 Jennifer Weida et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. As more women with metabolic muscle diseases reach reproductive age, knowledge of these diseases and their impact on pregnancy is necessary. Case. 23-year-old G1P0 with juvenile-onset Pompe disease (PD) delivered a viable infant by cesarean section at 32 weeks and 6 days. The pregnancy was complicated by worsening maternal pulmonary status, muscular strength, and mobility. Conclusion. The management of pregnancies complicated by Pompe disease requires a multidisciplinary approach, including expertise in neuromuscular disease, maternal-fetal medicine, biochemical genetics, pulmonology, anesthesia, and dietetics.