Table 1: Reported cases of achalasia in pregnancy with the type of treatment and pregnancy outcome (from 1969 till 2010).

AuthorYearNumber of casesAge of pt/weeks gestationType of treatmentOutcome

Paulsen et al.2010134 yo/?Balloon dilationUncomplicated birth

Wataganara et al.2009139 yo/33 wBotulinum toxin35 w C-section

Diaz Roca et al.2009136 yo/26 wSelf expanding prosthesisUneventful delivery

Palavinelu et al.2008124 yo/2nd trimesterLaparoscopic Heller’s myotomyHealthy baby

Pulanic et al.2008130 yo/26 wPneumatic dilationVaginal delivery 38 w

Ohno et al.2000134 yo/27 wSurgical myotomy postpartumIntrauterine fetal death

Kalish et al.1999142 yo/31 wAntifungal medicationSpontaneous vaginal delivery 38 w

Fassina et al.1995123 yo/24 wUnexplained sudden maternal death (6-month pregnancy), megaesophagus

Fiest et al.1993124 yo/8 wBalloon dilationSpontaneous vaginal delivery 35 w (healthy infant)

Satin et al.1992128 yo/38 wPneumatic dilationInduced vaginal delivery 38 w (healthy infant)

Mayberry and
Atkinson
19872018 yo–45 yo
(mean 32 yo)/?
Comparison of reproductive histories of women with achalasia with those of a control groupNo significant difference in the number of live births of patients versus controls 3 miscarriages after diagnosis

Clemendor et al.19691022 yo–37 yo
(mean 29.1 yo)/24 w–30 w
1case Pneumatic dilation (1st report)
5 cases Bougie dilation
3 cases medical treatment
1 case no treatment
Living offspring in only 5 cases (the rest: 2 terminations, 2 stillbirths, 1 premature delivery).