Brugada Syndrome and Pregnancy: Highlights on Antenatal and Prenatal Management

Table 1

Analgesic/anesthetic agent forbidden in Brugada patient (mod, 14).

Generic name	Clinical use/class	References	Recommendation
Bupivacaine	Analgesic agent/anesthetic	De La Coussave 1992 [16], Berman 1994 [17], Phillips 2003 [18], Vernogy 2006 [19], Bramall et al. 2011 [10]	IIa
Procaine	Analgesic agent	Arumugam 2012 [20]	IIa
Propofol	Anestehtic agent	Saint 1998 [21], Inamura 2006 [22], Vernogy 2006 [19], Robinson 2008 [23]	IIb

Leg: Class IIa: There is conflicting evidence and/or divergence of opinion about the drug, but the weight of evidence/opinion is in favor of a potentially arrhythmic effect in Brugada syndrome patients.
Class IIb: There is conflicting evidence and/or divergence of opinion about the drug, and the potential arrhythmic effect in Brugada syndrome patients is less well established by evidence/opinion.