Case Report

Serous Ovarian Carcinoma Recurring as Malignant Mixed Mullerian Tumor

Table 1

Clinicopathological and clinical characteristics of ovarian cancer patients recurring as carcinosarcoma, as reported in the literature.

AuthorAge [year]Primary surgerySide, histology, and grade of primary tumorStageSite of recurrenceAt diagnosis of recurrence treatmentDiagnosis of recurrent tumorSurvival from recurrence

Domoto et al. 2000 [4]49TAH + BSO + partial omentectomy + dissection of para-aortic lymph nodes + ascitic fluidBilateral ovaries, serous,
not available
IIIcInguinal lymph nodesSurgery followed by chemotherapyCarcinosarcoma [heterologous type]Alive after 16 months

Moritani et al. 2001 [5]62Right salpingo-oophorectomyRight ovary, endometrioid, GIIIIAbdominalSurgery followed by chemotherapyCarcinosarcoma [heterologous type]Alive after 6 months

Gallardo et al. 2002 [6]
 Case I71TAH + BSOLeft ovary, serous, high gradeIIIcPelvicSurgery followed by chemotherapyCarcinosarcoma [heterologous type]Died several months after the second chemotherapy
 Case II78Not availableLeft ovary, serous, high gradeIPelvicSurgery followed by chemotherapyCarcinosarcoma [heterologous type]No further clinical follow-up

Ferrandina et al. 2007 [7]52TAH + BSO + omentectomy + appendectomy + pelvic and aortic lymphadenectomy + peritoneal washing + multiple biopsiesBoth ovaries, serous, GIIIIIIcAbdominalSurgery followed by chemotherapyCarcinosarcoma [heterologous type]Alive after 9 months

Current case64TAH + BSO + omentectomy + peritoneal washing + inguinal hernia excision + multiple biopsiesLeft ovary, serous, GIIIIIIcAbdominal and subcutaneous tissueSurgery followed by chemotherapyCarcinosarcoma [homolog type]Alive after 3 months