Serous Tubal Intraepithelial Carcinoma: An Incidental Finding at the Time of Prophylactic Bilateral Salpingo-Oophorectomy

Figure 1

(a) H&E stain of the distal fimbriated end of the left fallopian tube. At low magnification, the area of STIC demonstrates increased epithelial thickness and nuclear stratification compared to areas of normal tubal epithelium. (b) Area of STIC with nuclear stratification and moderate variability in size and shape. Also note the absence of ciliated cells within the lesional area. (c) At high magnification, nuclear atypia is clearly visible, including hyperchromatism, prominent nucleoli, loss of polarity, and increased mitotic figures. (d) Strong and diffuse nuclear TP53 staining of STIC.

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