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Author | Disease history | Treatment | Maternal outcome | Fetal outcome |
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Katzir et al. [3], 2004 | 23 y/o with known MGN | Methylprednisolone pulse therapy Oral prednisolone | Proteinuria, HTN Preeclampsia at 34 weeks HTN, proteinuria resolved following delivery | C/S at 34 weeks, secondary failed induction for preeclampsia Male, 2,090 g |
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Sebestyen et al. [9], 2008 | 33 y/o with known MGN Previous pregnancy with preeclampsia at 36 weeks | Methylprednisolone pulse therapy Oral prednisolone Azathioprine | Deterioration of creatinine clearance, low serum total protein, increasing edema Three months after delivery, maternal condition went into complete remission | IUGR C/S at 33 weeks due to IUGR and deterioration of maternal renal function Male, 1,160 g |
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Aoshima et al. [10], 2013 | 37 y/o, no history of MGN Previous normal pregnancy | Methylprednisolone pulse therapy Oral prednisolone | Increasing edema Increasing proteinuria 5.28 g/day Diagnosed with MGN at after pregnancy termination Symptoms resolved after termination | Elective termination due to worsening symptoms at 21 weeks |
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Ope-Adenuga et al., index patient | 28 y/o, no history of MGN First pregnancy: uncontrolled HTN Second pregnancy: uncomplicated Third pregnancy: possible preeclampsia, fetal demise at 29 weeks Fourth pregnancy: index case | Tacrolimus Oral prednisone | Increasing edema, worsening of renal function, increased proteinuria Diagnosed with MGN at 25-week gestation Symptoms improved during treatment and completely resolved after delivery | Preterm labor at 30 weeks Female, 1021 g |
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