Prenatal Diagnosis of WAGR Syndrome

Figure 2

Fetal MRI images of absent corpus callosum and the picture of the newborn. (a) Axial scans at the level of the atria and bodies of the lateral ventricles show bilateral posterior ventriculomegaly. Anteriorly the lateral ventricles are narrow and parallel. This is the appearance of colpocephaly which is characteristically associated with ACC. (b) Coronal MRI scan at the level of third ventricle shows agenesis of the corpus callosum. The bodies of the lateral ventricles have a lateral convexity in the coronal plane and a medial concavity due to the presence of Probst’s white matter bundles. This is the typical appearance in callosal agenesis. (c) Midsagittal MRI scan confirms absence of the corpus callosum. (d) Photograph taken in the postnatal period.

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