Case Report
Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries
Table 1
Characteristics of inherited fibrinogen disorders.
| ā | Afibrinogenemia | Hypofibrinogenemia | Dysfibrinogenemia |
| Transmission | AR | AD/AR | AD |
| Fibrinogen level (mg/dL) | <10 | 70ā100 | Lower limit of normal |
| Laboratory | PT-APTT-TT | PT: normal or prolonged | PT-APTT: normal | Markedly prolonged | APTT: normal |
| Symptoms | Umbilical cord bleeding | No symptoms Abnormal bleeding after trauma or operation | No symptoms Abnormal bleeding after trauma or operation Thrombosis | Recurrent abortion | Cutaneous bleeding | Intracranial bleeding | Gastrointestinal bleeding | Hypermenorrhea |
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AR; Autosomal recessive, AD; Autosomal dominant, PT; prothrombin time, APTT; actinated partial thromboplastin time, TT; thrombin time.
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