Case Report

Small Cell Neuroendocrine Carcinoma of the Cervix in Pregnancy: A Case Report and Review

Table 1

Small cell neuroendocrine cervical cancer during pregnancy: literature review.

AuthorAgeFIGOParity GANACT TreatmentFollow upOutcome
(years)stage(weeks)(months)

Teefey31IB1G2P1104EPC/S+RH+PLND 24NED
Wu25IB1G1P0term2IEPRT+PLND+6IEP 84NED
Wang18IB2G1P1term4EPRadiotherapy 5NED
Chun27IB1253TPC/S+RH+PLND+PALND 46DOD
Chun32IIA281TCRH+PLND+PALND 48NED
Chun27IB2282TPRH+PLND+PALND+4TP 60NED
Smyth26IIAG1P0233ACC/S+4EP+ RadiationNED
Ohwada27IB1G1P027C/S+RH+PLND+4EP 13NED
Leung26IB2G1P031C/S+CCRT+LH+BSO 14NED
Balderston22IIAG5P3303EPRadiation+4EP 66NED
Perrin23IIAG1P025C/S+RH+LSO+PLNDDOD
Chang27IB36C/S+RH+PLNDDOD
Lojek28IIA25C/S+PLND+CCRT 30DOD
Turner26IBG2P126C/S+RH+PLND+6VAC+2EP 9DOD
Jacobs25IB10DDPRH +PLND +Radiotherapy 24DOD
Kodousek29IB28C/S+RH+PLND+EP 6DOD
Canto30IV-BG1P0361EP 1DOD
Liu25IV-B32C/S+RH+PLND 3DOD

FIGO, International Federation of Gynecology and Obstetrics; GA, gestational age; NACT, neoadjuvant chemotherapy; EP, cisplatin+ etoposide; TP, Paclitaxel+ Cisplatin; TC, Paclitaxel+carboplatin; VAC,vincristine+doxorubicin+ cyclophosphamide; IEP, ifosfamide+ cisplatin+ etoposide; C/S, cesarean section; RH, radical hysterectomy; RT, Radical Trachelectomy; PLND, pelvic lymph node dissection; PALND, para-aortic node dissection; CCRT, chemoradiotherapy; DOD, dead of disease; NED, no evidence of disease.