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Case Reports in Oncological Medicine
Volume 2012 (2012), Article ID 232851, 3 pages
http://dx.doi.org/10.1155/2012/232851
Case Report

Double Feature: Carcinoma and Sarcoma Present in a Single Breast Tumor

Department of General Surgery and Department of Family Medicine, West Virginia School of Osteopathic Medicine, 400 North Lee Street, Lewisburg, WV 24901, USA

Received 17 July 2012; Accepted 27 August 2012

Academic Editors: Y. Aoki and A. Kolacinska

Copyright © 2012 Catherine M. Stefaniuk and Timothy Jones. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Primary breast sarcomas (PBSs) are rare nonepithelial breast tumors compromised of mesenchymal mammary tissue. Although its rare nature has made the best mode of PBS treatment difficult to determine, it seems better to treat it more like a sarcoma creating clear negative margins verses breast carcinoma utilizing lumpectomy, partial mastectomy, and total mastectomy. Case. A 47-year-old obese Caucasian postmenopausal female G2P2 presents with a breast lump demonstrating a histological sample with a biphasic pattern consistent with both ductal carcinoma containing typical malignant epithelial cells and sarcomatous differentiation of carcinosarcoma. Conclusion. Carcinosarcoma is a rare breast malignancy. Sarcomas of the breast tend to be negative for estrogen receptor and lack known risk factors. Current recommended treatment is to treat breast sarcomas like other soft tissue sarcomas by performing wide local excision instead of partial mastectomy. Antiestrogens and other chemotherapeutic agents typically used in breast epithelial malignancies are not recommended since these sarcomas tend to be negative with these receptors.