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Case Reports in Oncological Medicine
Volume 2012 (2012), Article ID 823042, 3 pages
Case Report

Metastasis of Renal Cell Carcinoma to the Buccal Mucosa 19 Years after Radical Nephrectomy

Servicio de Urología, Hospital Universitario Virgen de las Nieves, 18012 Granada, Spain

Received 16 July 2012; Accepted 3 October 2012

Academic Editors: T. Arkenau, G. G. Chung, and R. Martinez

Copyright © 2012 Hernani Gil-Julio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Renal cell carcinoma (RCC) has high metastatic potential, which requires early diagnosis to optimize the chance of cure. Metastasis of RCC to the head and neck region is less common and metastasis to the buccal mucosa is extremely rare. This phenomenon occurs mostly in patients with generalized dissemination, especially with lung metastases. In this article we report a case of buccal mucosa metastasis from RCC in a 65-year-old man who presented 19 years after undergoing a left radical nephrectomy for clear cell RCC. Surgical excision of the buccal lesion was performed without evidence of recurrence or new metastatic lesions after 6 years of followup. To our knowledge, this is the first case of metastasis to the buccal mucosa from a RCC reported in the literature.