A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases

Table 2

Somatic copy-number aberrations.

Gene	Chr	Start coordinate	End coordinate	Adjusted mean log ratio	𝑃 value	Adjusted 𝑃 value	Gain/loss
AAK1	2	69752135	69752264	1.719	1.76𝐸−006	1.54𝐸−002	Gain
ABCA1	9	107586742	107586862	1.908	1.50𝐸−007	2.40𝐸−003	Gain
ABCA12	2	215890389	215890509	1.846	7.60𝐸−006	3.83𝐸−002	Gain
AGAP1	2	236791980	236792100	2.084	6.34𝐸−009	1.35𝐸−004	Gain
ALDH1A1	9	75533626	75533746	1.595	5.94𝐸−006	3.25𝐸−002	Gain
ASAP2	2	9508540	9508660	1.931	1.08𝐸−006	1.13𝐸−002	Gain
CDKN2A	9	21974440	21974830	−4.943	1.48𝐸−031	1.42𝐸−026	Loss
CERKL	2	182430138	182430258	1.672	1.12𝐸−006	1.13𝐸−002	Gain
CLASP1	2	122098419	122098539	1.990	2.29𝐸−008	4.38𝐸−004	Gain
ETV5	3	185823397	185823517	−1.623	4.52𝐸−006	2.71𝐸−002	Loss
EXD3	9	140250649	140250877	1.883	1.22𝐸−005	4.65𝐸−002	Gain
GABBR2	9	101156436	101156556	1.864	9.79𝐸−008	1.70𝐸−003	Gain
GSN	9	124076166	124076316	1.636	8.28𝐸−006	3.96𝐸−002	Gain
IL18RAP	2	103040817	103040937	1.602	6.85𝐸−006	3.64𝐸−002	Gain
INPP4A	2	99136444	99136684	1.894	1.99𝐸−006	1.65𝐸−002	Gain
ITGA4	2	182388877	182388997	1.965	1.44𝐸−006	1.38𝐸−002	Gain
LOC375190	2	24390449	24390569	2.155	1.82𝐸−007	2.68𝐸−003	Gain
LOC96610	22	22657565	22657685	1.907	1.01𝐸−005	4.29𝐸−002	Gain
MERTK	2	112765945	112766169	1.473	7.37𝐸−006	3.81𝐸−002	Gain
MERTK	2	112778145	112778265	1.707	9.88𝐸−006	4.29𝐸−002	Gain
MFSD6	2	191354482	191354602	1.980	5.64𝐸−007	6.35𝐸−003	Gain
MTAP	9	21837897	21838017	−4.841	4.56𝐸−045	8.72𝐸−040	Loss
NGEF	2	233745847	233745967	1.612	8.93𝐸−006	4.17𝐸−002	Gain
NUP188	9	131719210	131719330	1.627	2.65𝐸−006	2.03𝐸−002	Gain
POLR1E	9	37489294	37489414	2.029	2.27𝐸−007	3.10𝐸−003	Gain
POMT2	14	77753065	77753185	1.796	3.35𝐸−006	2.46𝐸−002	Gain
PPIG	2	170460673	170460793	1.944	2.96𝐸−007	3.77𝐸−003	Gain
PPP1R13B	14	104201451	104201571	−1.855	3.88𝐸−006	2.48𝐸−002	Loss
PSMD5	9	123591371	123591491	1.845	9.39𝐸−006	4.28𝐸−002	Gain
RNASEH1	2	3596211	3596331	1.911	5.03𝐸−006	2.83𝐸−002	Gain
SH3RF3	2	109988029	109988149	2.909	2.23𝐸−013	7.12𝐸−009	Gain
SLC46A2	9	115642010	115642130	1.621	1.14𝐸−005	4.45𝐸−002	Gain
SULT6B1	2	37415566	37415686	1.530	1.04𝐸−005	4.32𝐸−002	Gain
TESK1	9	35607906	35608026	1.688	4.54𝐸−006	2.71𝐸−002	Gain
TTC27	2	32929895	32930015	1.466	1.09𝐸−005	4.43𝐸−002	Gain

Chr: chromosome, bolded genes are in cosmic v61.