Author Age/ Gender Type of MM Ca (mg/dL) Therapy for MM and PHPT Parathyroid histology Outcome Initial diagnosis 1
Pest et al. [1 ] 76 F IgA-? 13.2 Hydration, bisphosphonates, Lasix, melphalan, cyclophosphamide, and steroids Adenoma Survived PHPT 2
Rao et al. [2 ] 54 M IgG-lambda 11.2 Adriamycin, melphalan, prednisone, cyclophosphamide, and parathyroidectomy Adenoma Died after 12 years Both 3
Jackson and Orland [3 ] 45 F IgG-lambda 17.1 Hydration, Lasix, prednisone, and melphalan Adenoma — MM 4
Chisholm et al. [4 ] 80 M Kappa 13.1 Parathyroidectomy, radiotherapy, melphalan, prednisone, vincristine, carmustine, cyclophosphamide, hydration, and Lasix Adenoma (c-cells) Died 2 years later PHPT 5
Francis et al. [5 ] 70F Lambda 11.6 Norethisterone, vincristine, melphalan, and prednisone Adenoma Died 3 weeks later PHPT 6
Mundis and kyle [6 ] 76 F IgG-kappa 11.0 Melphalan, prednisone, and parathyroidectomy Adenoma (c-cells) survived MM 7
Stone et al. [7 ] 47 F IgA-kappa 13.7 Melphalan, prednisone, radiotherapy, parathyroidectomy, hydration, and mithramycin Adenoma Died MM 8
Hoelzer and Silverberg [8 ] 51 F IgA-lambda 11.9 Parathyroidectomy? Adenoma (c-cells) — PHPT 9
Schneider and Thomas [9 ] 74 F IgG-kappa 12.0 Melphalan, prednisone, and parathyroidectomy Adenoma Survived MM 10
Toussirot et al. [10 ] 82 M Kappa 15.2 Melphalan, prednisone, and parathyroidectomy Hyperplasia Died PHPT 11
Goto et al. [11 ] 73 F Kappa 13.2 Parathyroidectomy, melphalan Adenoma Died 1 year later PHPT 12
Otsuka et al. [12 ] 77 F IgG-lambda Melphalan, prednisone, bisphosphonates, calcitonin, and parathyroidectomy c-cells hyperplasia Survived — 13
Fery-Blanco et al. [13 ] 68 F IgG-kappa 11.28 ? chemotherapy and surgery refused Adenoma Died Both 14
Sarfati et al. [14 ] 62 F IgA-kappa 16.4 Mithramycin, lasix, plasmaphoresis, Adriamycin, vincristine, prednisone, and parathyroidectomy Adenoma Survived MM 15
Rosen et al. [15 ] 81 M IgG-kappa 13.4 Hydration, bisphosphonates, melphalan, prednisone, radiotherapy, needle aspiration of parathyroid gland, and refused surgery Adenoma Survived MM 16
Tomon et al. [16 ] 60 F IGA-kappa — — — — MM 17
Fanari et al. [17 ] 59 F lambda 12.7 Hydration, bisphosphonates, cinacalcet, bortezomib and dexamethasone Possible Adenoma Died 4 months later Both 18
Bogas et al. [18 ] 72 F IgG-kappa 13.66 Melphalan, prednisone, and Interferon? Adenoma Died 4 years later Both 19
Katayama et al. [19 ] 50 F PHPT 20
Romagnoli et al. [20 ] 70 F — — Parathyroidectomy, steroids and chemotherapy Adenoma — PHPT (MEN-1) 21
Toh and Winocour et al. [21 ] 71 M 12.0 Melphalan, prednisone, and bisphosphonates Died 6 weeks later MM 22
Sope
a et al. [22 ] 77 F Kappa (ns) 12.9 Bisphosphonates, refused surgery, or chemotherapy Died 1 year later Both 23
Khandwala and Boctor [23 ] 72 F — 11.7/ 16.6* Parathyroidectomy, bisphosphonates, calcitonin, melphalan, and prednisone Adenoma — PHPT 24
Patel et al. [24 ] 73 F IgG- kappa 13.5 Bisphosphonates, steroids, thalidomide, plicamycin, and parathyroidectomy Adenoma — MM 25
Avcioglu et al. [25 ] 52 F IgG-kappa 12.6 Parathyroidectomy and steroids Adenoma — Both 26
Chowdhury and Scarsbrook et al. [26 ] 87 F — — — — — PHPT 27
Dalgleish and Gatenby [27 ] 59 F IgG-lambda 11.68 Hydration, lasix, prednisone, mithramycin, cyclophosphamide, and parathyroidectomy Adenoma Survived MM 28
Peters et al. [28 ] 73 M IgA-lambda 16 Parathyroidectomy, chemotherapy, and radiotherapy Hyperplasia Died 1 week later PHPT 29 Our case 92 F IgG-kappa 13 .3 Bisphosphonates, Lasix, hydration, calcitonin, melphalan, prednisone, lenalidomide, and dexamethasone — Survived Both 30
Johansson and Werner [29 ] mentioned 3 cases of MM and PHPT (no detail of the cases is given), one other such as has been described by
Drezner and Lebovitz [30 ] without much detail.
