Case Report
Primary Isolated Lymphoma of the Fourth Ventricle in an Immunocompetent Patient
Table 1
Summary of the reported cases of 4th ventricular PCNSL in the literature.
| Author (reference) | Age (yrs)/sex | Presentation | Radiology | Surgical treatment | CSF cytology | Adjuvant therapy | Survival |
| Werneck et al. [3] | 17/F | Meningitis, diagnosis after mortem | Negative radiology but after mortem small tumor was found with carcinomatous meningitis | N/A | Positive | N/A | Diagnosis after mortem |
| Haegelen et al. [4] | 33/F | Headache, vomiting with cerebellar signs | Tumor filling the 4th ventricle with no HCP | GTR | Negative | Cytarabine and steroids with stem cell transplantation with WBRT | 7 months |
| Hill et al. [5] | 69/F | Headache, vomiting | Homogenously enhancing tumor in the caudal fourth ventricle without hydrocephalus | Biopsy | N/A | IV and IT MTX | 3 months |
| Current case | 50/M | Headache, vomiting with drowsiness | Homogenously enhancing tumor in the caudal fourth ventricle with hydrocephalus | GTR | Negative | Regimen containing IV and IT MTX and radiotherapy | 18 months |
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GTR: gross total resection; IV: intravenous; IT: intrathecal; MTX: methotrexate; N/A: not available.
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