Case Report

Bilateral Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Breast: A Very Rare Entity and Review of the Literature

Table 1

Summary of primitive neuroectodermal tumors of the breast reported in the literature.

ReferenceAge
(years)
PresentationSize (cm)DiseaseTreatmentOutcome

Tamura et al. [2]47Breast lump 2.1 1.8PrimaryMastectomyNot available

Maxwell et al. [3]35Breast lump 1.8PrimaryLumpectomy
+ chemotherapy
Free of disease at 2.5 years

da Silva et al. [4]35Breast lump12 7.5PrimaryChemotherapy
+ radiotherapy
Local and pulmonary relapse; death at 2 years

Ko et al. [5]33 Breast lump 2.5 2PrimaryLumpectomyFree of disease at 6 months

Vindal and Kakar [6]26Breast lump PrimaryWide local excision
+ adjuvant chemotherapy
Free of disease at 36 months

Kwak et al. [7]49Mass in the axillaMetastaticChemotherapyNot available

Dhingra et al. [8]26Breast lump 3.5 3PrimaryMastectomy
+ chemotherapy
+ radiotherapy
Free of disease at 12 months

Suebwong et al. [9]46Breast lump4PrimaryChemotherapy
+ radiotherapy
Local and pulmonary progression

Majid et al.30Bilateral breast lump7 and 5 in the right and left, respectivelyMetastaticChemotherapyThe patient’s medical
condition deteriorated, and she died after 2 cycles of chemotherapy