Clear Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature
Figure 1
Histologic appearance of the clear cell adenocarcinoma of the colon. (a) H&E slide demonstrates rare variant of colonic adenocarcinoma with clear cell features. It shows gland-forming invasive tissue composed of columnar cells with unusually clear cytoplasm, prominent nucleolus, and central necrotic debris (400x). (b) Immunohistochemistry shows a strongly CDX2 positive staining of the malignant tissue (40x).