A Unique Presentation of Occult Primary Breast Cancer with a Review of the Literature

Table 1

Summary of literature reviewed on occult primary breast cancer.

	Median F/U (yr)	Patients	Overall survival		Recurrence-free survival		Locoregional recurrence	Distant recurrence
			5 yr OS	10 yr OS	5 yr RFS	10 yr RFS
Vlastos et al. (2001) [1]	7.0	BCT: 32	79%	64%	72%	63%	13%	22%
		Mast: 13	75%	66%	67%	56%	15%	31%
Galimberti et al. (2004) [2]	3.4	50	—	—	—	—	4%	12%
Walker et al. (2010) [3]	4.0	BCT: 202		67.1%	—	—	—	—
		Mast: 268	—	63.5%	—	—	—	—
		ALND: 126	—	58.5%^*	—	—	—	—
		Obs: 94	—	47.5%^*	—	—	—	—
He et al. (2012) [4]	3.2	BCT: 13	—	—	—	—	8%	15%
		Mast: 64	—	—	—	—	11%	6%
		ALND: 18	—	—	—	—	28%	6%
Campana et al. (1989) [5]	9.0	31	76%	71%	86%	75%	25%	29%
Foroudi and Tiver (2000) [6]	9.2	BCT: 12	—	—	—	—	25%	0%
		Mast: 2	—	—	—	—	0%	0%
		Obs: 6	—	—	—	—	83%	—
Barton et al. (2011) [7]	5.7	BCT: 35	84%	—	64%	—	14%	—
		No RT: 13; (nodal and/or partial breast resection)	85%	—	34%^*	—	85%	—

(i) Statistically significant value.
(ii) BCT: breast conserving therapy, RT: radiotherapy, Mast: mastectomy, ALND: axillary lymph node dissection, and Obs: observation.
(iii) OS: overall survival, RFS: recurrence-free survival, F/U: follow-up period, and mo: month.
(iv) —: not reported.