Clinicopathological and Targeted Exome Gene Features of a Patient with Metastatic Acinic Cell Carcinoma of the Parotid Gland Harboring an ARID2 Nonsense Mutation and CDKN2A/B Deletion

Figure 4

The protein domain arrangement in ARID2 protein. ARID2 has four discrete domains: the ARID domain (residues 14–101), the RFX domain (residues 523–582), the GLN domain (residues 793–1128), and a domain that contains two ZnFs (1634–1690). The red arrow indicates the approximate location of the nonsense mutation identified in the AciCC of the patient.