Metastatic Breast Carcinoma to the Prostate Gland

Figure 2

Prostate needle core biopsy shows infiltrative nests of hyperchromatic nuclei with modest eosinophilic cytoplasm separated by fibrous stroma with a desmoplastic reaction on H&E. Immunohistochemical stains show nuclear staining for ER and GATA3 and negative staining by PSA.