| Authors | Age | Receptors | Concurrent diagnoses/presentation/notes | E-cad loss | Imaging | Time from 1° Dx | Histology | Ref |
| Jungst et al., 2013 | 70 | NA | Diabetes, variceal bleeding | NA | Cirrhosis on MRI, no focal lesion | 7 yr | Ductal+lobular | [13] | Allison et al., 2004 | 42 | ER-, PR- | Tobacco abuse, thrombocytopenia | Yes | Not performed | 0 yr | Poorly differentiated | [9] | Allison et al., 2004 | 54 | NA | Ascites, jaundice, hematochezia | Yes | Multiple masses on CT | 9 yr | Poorly differentiated | [9] | Allison et al., 2004 | 36 | NA | Nausea/vomiting/abd pain and jaundice | Yes | Small masses on CT | 9 mo | Poorly differentiated | [9] | Hanamornroongruang and Sangchay, 2013 | 49 | ER+, PR+ | Weight loss, jaundice, abd pain | Yes | CT without mass | 10 yr | Ductal, stage I | [2] | Martelli et al., 2000 | 53 | ER+, PR+ | Dyspnea, fever | NA | Hepatomegaly on US | 4 yr | Ductal | [3] | Mogrovejo et al., 2014 | 67 | ER+, PR-, HER2- | Fatigue, weakness, abdominal distention/jaundice, lower extremity edema | No | CT ascites | 21 yr | Ductal+lobular | [4] | Borja et al., 1975 | 46 | NA | Jaundice, ascites, spider angiomata | NA | CT cirrhosis | 3 mo | Poorly differentiated | [5] | Graber et al., 2010 | 57 | ER+, PR+, HER2+ | Hyperthyroid, ascites, thrombocytopenia, hyperbilirubinemia | Yes | CT/US w/o mass, heterogeneous parenchyma | 0 yr | Lobular | [6] | Fournier et al., 2010 | 52 | ER+, PR-, HER2- | Bone mets from breast cancer, abdominal fullness | NA | CT with ascites, splenomegaly, but no liver abnormality | 5 yr | Ductal, stage II | [10] | Goswami et al., 2011 | 38 | ER-, PR+, HER2+ | Malaise, lethargy, sore throat, dyspnea | NA | CT hepatomegaly, periportal nodes | 0 yr | Ductal, grade 2 | [11] | Morrison and Pennington, 1984 | 57 | NA | Rapid fulminant hepatic failure | NA | NA | 0 yr | Carcinoma NOS | [14] | Nakajima et al., 2005 | 68 | NA | Drowsiness, disorientation, lymphangitic cancer spread to lungs | NA | CT normal liver, laparoscopic slight cirrhosis | 8 mo | Ductal, stage I | [15] | Nascimento et al., 2001 | 62 | NA | Ascites, edema | NA | US w/o mass, reversal of portal flow, MRI w cirrhosis | 13 yr | NA | [16] | Nascimento et al., 2001 | 46 | NA | Nausea, vomiting, abdominal girth increase, disseminated intravascular coagulopathy | NA | CT neg for lesions, MRI w cirrhosis | 5 yr | Mucinous, poorly differentiated | [16] | Sass et al., 2007 | 55 | ER+, PR-, HER2- | Jaundice, dark urine, acholic stool, and abdominal distension | NA | CT nodular contour c/w cirrhosis, no focal lesion | 4 yr | Ductal, stage I | [17] | Shivashankar and Sweetser, 2012 | 66 | ER+, PR+ | Abdominal distention, hepatomegaly | NA | CT with cirrhosis, but no mass | 8 yr | NA | [18] | Current case | 69 | ER+, PR+, HER2- | Bone mets from breast cancer, no presenting symptom, eventual leptomeningeal metastases | Yes | Cirrhosis on CT, US and MRI | 9 yr | Ductal | |
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