Fulminant Disseminated Intravascular Coagulation as Initial Presentation of BRAF-Mutated Melanoma

Table 1

Case reports of metastatic melanoma presenting with DIC.

Source	Clinical presentation	Diagnosis	Treatment course	Citation
Bhattacharyya et al.	62-year-old woman presenting with hematuria and DIC 2 months after she was diagnosed with BRAF-mutated metastatic melanoma.	BRAF-mutated metastatic melanoma	DIC improved with vemurafenib.	[1]
Lepelley-Dupont et al.	61-year-old woman with history of metastatic melanoma presenting with acute hemorrhagic shock with evidence of DIC.	Metastatic melanoma	Dacarbazine was started; however, patient expired secondary to hemorrhagic shock.	[2]
Schlaeppi et al.	37-year-old man with history of excised melanoma 6 years ago found to have diffuse metastatic disease of the liver and DIC.	Metastatic melanoma	DIC resolved with dacarbazine, vinblastine, and cisplatine.	[3]