Choroidal Metastasis of Non-Small Cell Lung Cancer That Responded to Gefitinib
Figure 1
(a) Photograph of fundoscopy in the involved eye (left-side) before gefitinib treatment. A large elevated lesion in the superotemporal quadrant was found (arrows) with exudation. The patient’s best corrected visual acuity in the left eye was 20/200 before treatment. (M: macula). (b) The elevated lesion disappeared a month after the onset of gefitinib treatment. Her best corrected visual acuity in the left eye improved to 20/100 after treatment. (c) Optical coherence tomography (OCT) before treatment corresponding to (a). A dome-shaped large mass with high reflectivity occupied the choroid, pushing the retina into the vitreous-cavity side (arrows). Accumulation of the subretinal fluid was also observed. (C: choroid, F: fovea centralis, R: retina, SRF: subretinal fluid, V: vitreous body). (d) Complete flattening of the tumor and decreased subretinal fluid were observed, demonstrating a dramatic response to gefitinib.
