Tolerance to Systemic Isotretinoin Therapy in Two Patients Using Highly Wettable Contact Lenses

Table 1

OSDI questionnaire and tear function test results of the patients.

	OSDI		Schirmer without anaesthesia (mm)		Schirmer with anaesthesia		TBUT (seconds)
Measurement time	Case  1	Case 2	Case  1	Case  2	Case  1	Case  2	Case  1	Case  2
Before treatment	4.17	4.17	35-34	33-33	25-24	23-23	20-20	25-26
At the 2nd month of treatment	4.17	4.17	30-30	27-26	22-22	18-18	15-15	16-16
At the 6th month of treatment	4.17	6.25	23-23	20-19	17-18	14-13	13-13	13-13
One month after completing treatment	4.17	4.17	35-35	35-35	25-25	24-23	20-20	25-25

OSDI: ocular surface disease index; TBUT: tear break up time.