Epithelial Downgrowth after Intraocular Surgery Treated with Intracameral 5-Fluorouracil

Figure 2

(a) Slit lamp photograph of the right eye showing epithelial downgrowth (EDG) involving the temporal aspect of the cornea (border indicated by arrow). (b) Four months after the 5FU injections, there was no clinical evidence of EDG, but there was significant corneal edema secondary to endothelial decompensation. (c) DSAEK specimen showing rare epithelial cells on the posterior surface of host cornea. (d) EDG on the posterior surface of a portion of the DSAEK graft shows immunoreactivity for cytokeratin marker AE1/AE3. (c) H&E ×50, (d) IHC for AE1/AE3, ×250.

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