Novel Surgical Treatment for Refractory Heel Ulcers in Werner’s Syndrome

Table 1

Findings in Werner’s syndrome.

Characteristic feature of Werner’s syndrome
(1) Arrest of growth at puberty
(2) Development of senile cataracts in the third to fourth decade
(3) Premature graying (canities) and balding
(4) Scleroderma-like involvement of the extremities
(5) Marked diminution of the muscle mass and subcutaneous tissue of the extremities
(6) Chronic, slow-healing ulcerations over pressure points of the feet and ankles
(7) Beak-shaped nose
(8) Premature development of arteriosclerosis
Additional frequent manifestations of Werner’s syndrome
(1) Impaired carbohydrate tolerance
(2) Hypogonadism
(3) Osteoporosis
(4) Localized soft-tissue calcification
(5) History of consanguinity and familial incidence, or both
(6) Thin, high-pitched voice
(7) Circumscribed hyperkeratosis
(8) Multiple, recurrent, and painful callosities