Solitary Fibrous Tumor of the Lumbar Spine: The Great Mimicker—Report of the Fifth Case

Table 2

MSFT and other dural-based tumors: common and distinctive features.

	Common features	Different features
Fibrous meningioma	Imaging; Gross appearance; Spindle-shaped cells with abundant intercellular collagen	EMA+ and S-100+ CD34− or weak; Well-formed desmosomes; Genetic features: loss of DNA on chromosome 22, increase in neurofibromatosis type 2
Hemangiopericytoma	Vimentin+; Leu-7+	Aggressive neoplasm with tendency for recurrences and metastases; More densely cellular tumor; Polygonal cells with oval nuclei and scant cytoplasm
Myofibroblastoma	Benign; Derives from meningeal myofibroblasts	Vimentin+++; Smooth-muscle actin+
Fibrosarcoma	Arises in the meninges and sometimes in the intracerebral perivascular tissue	Malignant and aggressive, responds poorly to treatment; Anaplastic, mitotically active cells
Schwannoma	Spindle-shaped cells; CD34+ in 89% of cases	Antoni A and B histological patterns