Nodular Lymphocyte-Predominant Hodgkin Lymphoma in Progressive Transformation of Germinal Centers

Figure 1

(a) Low-power H&E staining showing prominent nodules in the background of reactive lymphoid tissue. (b) Interspersed large “popcorn” lymphocyte-predominant cells. (c) Large popcorn cells are positive for CD20. (d) CD3-positive T cells form rosettes around the large popcorn cells. (e) CD21 staining showing expanded follicular dendritic network in the large nodule.

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