Primary Small Cell Carcinoma of the Hypopharynx: A Report of Two Cases and Review of Nine Additional Cases

Figure 2

Histopathological and immunohistochemical features of the combined SmCC and SCC of the hypopharynx. (a) This tumor consists of a mixture of SmCC (center, arrow) and SCC (peripheral) (hematoxylin-eosin, original magnification 400x). (b) The p63 reactivity is seen in the nuclei of the cells of SCC but is not seen in SmCC component. (c) The CD56 reactivity in SmCC component is seen but is not seen in SCC component. (d) Chromogranin A shows positive cytoplasmic staining in SmCC component.

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