Primary Small Cell Carcinoma of the Hypopharynx: A Report of Two Cases and Review of Nine Additional Cases

Figure 5

Histopathological and immunohistochemical features of the combined SmCC and SCC of the hypopharynx. (a) SmCC component coexisting with SCC component accompanying keratinization (arrow) (hematoxylin-eosin, original magnification 200x). (b) The CD56 reactivity in SmCC component is seen but is not seen in SCC component. (c) The p63 reactivity is seen in the nuclei of the cells of SCC but is not seen in SmCC component. (d) Synaptophysin shows positive cytoplasmic staining in SmCC component.

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