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Number | Author | Year | Age/sex | Smoking | Stage (TNM) | Main symptom | Site | Extent of lesion at presentation | Histology | Locoregional TX | Adjuvant systemic TX | PCI | Metastases (observed throughout the course) | Follow-up |
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(1) | Ferlito and Polidoro | 1980 | 57/M | + | T1N2bM0 | Neck mass | PS | Locoregional | Combined with SCC | Radical S + RT | None | − | Cervical nodes, bone, soft tissue | Died of cancer 3.5 months after diagnosis |
(2) | Mills et al. | 1983 | 49/M | + | NA | Neck mass, dysphagia, weight loss | PS | Locoregional | Combined with SCC | Radical S + RT | None | − | Cervical nodes | Alive free of cancer 6 months after treatment |
(3) | Baugh et al. | 1985 | 63/F | − | T4a, more than N2c, M0 | Dysphagia, cervical mass | PS | Locoregional | Pure SmCC | Incomplete S | Many times (more than four) | − | Cervical nodes | Alive free of cancer 55 months after diagnosis |
(4) | Baugh et al. | 1985 | 35/M | − | T3N2aM0 | Dysphagia, weight loss | Base of tonsil to PS | Locoregional | Pure SmCC | RT | none | − | Cervical node | Alive free of cancer 21 months after diagnosis |
(5) | Gaba et al. | 2005 | 65/M | ex+ | T4aN1M0 | Dysphagia, weight loss | PS | Locoregional | Pure SmCC | Incomplete S + CRT | Many times (more than four) | − | Cervical node | Alive free of cancer more than 24 months after diagnosis |
(6) | Sano et al. | 2005 | 67/F | + | NA | Neck mass | PS | Locoregional | Pure SmCC | RT | Less than four | − | Cervical node, lung, liver | Died of cancer 13 months after diagnosis |
(7) | Uwa et al. | 2013 | 73/M | + | T4aN2bM0 | Neck mass | PS | Locoregional | Combined with SCC | Radical S | None | − | Cervical and mediastinum nodes, liver, lung | Died of cancer 9 months after treatment |
(8) | Bayram et al. | 2015 | 50/M | + | T4aN2bM1 (lung) | Severe respiratory distress | PS | Locoregional-distant | Pure SmCC | Incomplete RT | Less than four | − | Cervical and lung | Alive free of cancer 15 months after treatment |
(9) | Misawa et al. | 2016 | 74/M | + | T2N0M0 | Throat pain, hoarseness | PS | Local | Combined with SCC | CRT | None | − | Bone | Died of cancer 7 months after treatment |
(10) | Nakahira et al. | | 75/M | + | T2N2cM1 (bone) | Dysphagia | PS | Locoregional-distant | Combined with SCC | None | Many times (more than four) | − | Bone, liver | Died of cancer 6 months after treatment |
(11) | Nakahira et al. | | 73/M | − | T3N2bM0 | Dysphagia | PS | Locoregional | Combined with SCC | Radical S + RT | Many times (more than four) | + | Cervical nodes, lung | Alive with cancer 26 months after treatment |
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