A Novel del(20q) in Aggressive Nodal Marginal Zone Lymphoma

Figure 1

Histological features of lymph node. (A and B) Right posterior cervical lymph node, (A) H&E, 2x. The node is nearly completely effaced with minimal residual follicles. (B) H&E, 20x. Sheets of monocytoid cells in marginal zone. (C–F) Right cervical neck mass. (C) H&E, 60x. Sheets of monocytoid cells similar to those seen in the cervical lymph node. (D) H&E, 60x. Area of larger cells with focal necrosis. (E) H&E, 40x. Monocytoid cells and groups of larger cells (circle) with hyperchromasia. (F) MIB1 immunostain, 20x. Transformation areas with large cells show MIB-1 labeling index as high as 70%.