Cutaneous Epithelioid Clear Cells Angiosarcoma in a Young Woman with Congenital Lymphedema

Table 1

Clinical features of patients with cutaneous angiosarcoma associated with congenital lymphedema described in the literature (modified from Offori et al., 1993 [12] and Bernardi et al., 2009 [18] ).

Author	Sex	Age at diagnosis	Tumor site	Clinical appearance	Interval in diagnosis	Treatment	Survival
Kettle [19]	F	44 y	RL	Blue-red dislocation	Not stated	Amputation	Not stated
Liszauer et al. [20]	M	28 y	RLL	Ulcerated lesion	4 m	Local excision	Died at 11 m
Scott et al. [21]	F	50 y	LUL	Papillomatous nodules	>7 m	Local excision/amputation	Died at 37 m
Taswell et al. [22]	M	17 y	LUL	Ulcerated lesion	Not stated	Disarticulation	Died at 24 m
Bunch [23]	F	13 y	UL	Not stated	Not stated	Interscapular amputation	Died at 1 y
Finlay-Jones [24]	M	34 y	LLL	Ulcerated blue tumor	Not stated	Excision and combined therapy	Died at 31 m
Merrick et al. [25]	M	52 y	LUL	Swelling/blue nodules	6 m	Wide local excision/amputation/radiotherapy	Died at 36 m
Mackenzie [26]	M	64 y	RLL	Nodules/ulceration	2 m	Hindquarter amputation/radiotherapy	Alive at 24 m
Dubin et al. [27]	F	29 y	LUL	Ulcerated lesion	3 y	Disarticulation	Died at 45 m
Laskas et al. [28]	F	85 y	RUL	Purple papules and blisters/ulceration	10 m	Palliative midhumeral amputation	Died at 14 m
Banathy et al. [29]	F	50 y	LUL	Purple nodules	Not stated	Midhumeral amputation	Died at 26 m
Sordillo et al. [30]	F	23 y		Not stated	Not stated	Hemipelvectomy	Alive at 19 y
Bostrom et al. [31]	F	19 y	RUL	Infected lesion	4 m	Amputation/disarticulation	Died at 12 m
	F	10 y	LLL	Blue/red nodules	8 m	Amputation/disarticulation	Alive at 10 m
Offori et al., 1993 [12]	F	43 y	LLL	Blue/purple nodules	2 m	Amputation	Alive at 9 m
Andersson et al. [32]	M	35 y	RL	Blue nodules	Not stated	Hemipelvectomy, chemotherapy	Not stated
Cerri et al. [33]	F	42 y	Pubis	Ecchymotic plaque	Not stated	Hemipelvectomy, radiotherapy	Not stated
Bernardi et al. [18]	F	4 y	LLL	Ulcerated lesion/blue nodules	1 y	Local excision	Alive at 14 m
Deyrup et al., 2011 [14]	F	2 y	Foot	Not stated	Not stated	Local excision	Died at 1 y
Present case	F	21 y	Groin	Purple/reddish infiltrated and ulcerated mass	10 m	Local excision	Died at 3 m

LLL: left lower limb; RLL: right lower limb; LUL: left upper limb; RUL: right upper limb; m: months; and y: years.