Case Report
Intracranial Gliofibroma: A Case Report and Review of the Literature
Table 1
Clinical data and outcomes of patients with gliofibroma in the pediatric population published in the literature and the case presented here.
| Author/reference | Year | Age | Sex | Location | Surgery | Adjuvant therapy | Outcome (time of follow-up) |
| Friede [1] | 1978 | 3.9 yrs | F | Brainstem | Autopsy | RT CH | Died (3 mo) |
|
Iglesias et al. [2] | 1984 | 11 d | M | Spinal cord | PR | None | Alive (4 yrs) | Reinhardt and Nahser [9] | 1984 | 16 yrs | F | Hemispheric | CR | None | Alive (6 mo) |
| Snipes et al. [7] | 1991 | <2 mo | F | Posterior fossa/thalamus | PR | None | Died (16 mo) |
Vázquez et al. [8] | 1991 | 9 yrs | F | Spinal cord | PR | RT | Died (18 mo) | Vázquez et al. [8] | 1991 | 5.6 yrs | M | Spinal cord | PR | RT | Alive (2.5 yrs) | Vázquez et al. [8] | 1991 | 11 mo | F | Hemispheric | PR | None | Alive (2 yrs) |
| Schober et al. [6] | 1992 | 18 yrs | M | Hemispheric | CR | ND | ND | Iglesias-Rozas et al. [23] | 1992 | 1.2 yrs | F | Hemispheric | CR | None | Alive (18 mo) |
| Rushing et al. [15] | 1993 | 6 mo | F | IV ventricle | CR | None | Alive (2 yrs) | Cerda-Nicolas and Kepes [10] | 1993 | 9 yrs | M | Hemispheric | CR | ND | Alive (5.5 mo) | Cerda-Nicolas and Kepes [10] | 1993 | 4 yrs | F | IV ventricle | Bx | ND | ND |
| Windisch et al. [24] | 1995 | 5 mo | M | Spinal cord | PR | None | Alive (7 mo) | Caldemeyer et al. [21] | 1995 | 8 yrs | M | Hemispheric | ND | CH | Alive (ND) | Caldemeyer et al. [21] | 1995 | 6 mo | F | Cerebellum | CR | None | Alive (ND) |
| Prayson [25] | 1996 | 3 mo | M | Hemispheric | PR | None | Alive (3 yrs) |
| Mölenkamp et al. [26] | 1998 | ND | ND | ND | ND | ND | ND |
| Matsumura et al. [12] | 2002 | 12 yrs | F | Spinal cord | CR | ND | Alive (2.9 yrs) |
|
Suárez et al. [18] | 2004 | ND | ND | ND | Bx | CH | Alive (3 yrs) | Erguvan-Önal et al. [27] | 2004 | 16 yrs | M | Hemispheric | CR | None | Alive (14 mo) |
| Deb et al. [28] | 2006 | 15 yrs | ND | Brainstem | CR | None | ND |
| Goyal et al. [14] | 2007 | 8 yrs | M | Hemispheric | PR | RT CH | Alive (1 yrs) | Goyal et al. [14] | 2007 | 15 yrs | F | III ventricle | PR/CR |
RT(*) CH(*) | Alive (2 yrs) |
| Sarkar et al. [19] | 2009 | 3 mo | F | Lateral ventricles/III ventricle | Bx | None | Alive (10 yrs) |
| Altamirano et al. [22] | 2011 | 7 yrs | F | Thalamus/mesencephalon | PR | RT CH | Died (4 mo) |
| Gargano et al., this report | 2013 | 10.7 yrs | F | Hemispheric | CR | None | Alive (2 yrs) |
|
|
ND: no data; yrs: years; mo: months; d: days; F: female; M: male; CR: complete resection; PR: partial resection; Bx: biopsy; RT: radiation therapy; CH: chemotherapy. after second surgery.
|